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Synthesis of Novel Bispyrimido[1,2‐ b :1′,2′‐ e ][1,2,4,5]tetrazines
Author(s) -
Liebscher Jürgen,
Riemer Beate,
Hassoun Ahmed,
Stöβer Reinhard,
Grubert Lutz
Publication year - 1991
Publication title -
chemische berichte
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.667
H-Index - 136
eISSN - 1099-0682
pISSN - 0009-2940
DOI - 10.1002/cber.19911241221
Subject(s) - chemistry , perchloric acid , cyclic voltammetry , radical , acetic acid , bromine , condensation , medicinal chemistry , organic chemistry , electrochemistry , electrode , physics , thermodynamics
Novel bispyrimido[1,2‐ b :1′,2′‐ e ][1,2,4,5]tetrazines 3 are obtained by self‐condensation of 1‐amino‐2‐(methylthio)pyrimidinium iodides 1 . Zwitterionic bispyrimidines act as intermediates and can be isolated after short heating. Compounds 3 are oxidized with bromine or perchloric acid in acetic acid to give the corresponding radical salts 4 . These very stable radicals are characterized by ESR spectra and by cyclic voltammetry.