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Biocatalysis: Enzymatic Synthesis for Industrial Applications
Author(s) -
Wu Shuke,
Snajdrova Radka,
Moore Jeffrey C.,
Baldenius Kai,
Bornscheuer Uwe T.
Publication year - 2021
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.202006648
Subject(s) - biocatalysis , biochemical engineering , speciality chemicals , organic synthesis , scalability , scale (ratio) , nanotechnology , chemistry , management science , computer science , catalysis , organic chemistry , engineering , materials science , ionic liquid , physics , quantum mechanics , database
Biocatalysis has found numerous applications in various fields as an alternative to chemical catalysis. The use of enzymes in organic synthesis, especially to make chiral compounds for pharmaceuticals as well for the flavors and fragrance industry, are the most prominent examples. In addition, biocatalysts are used on a large scale to make specialty and even bulk chemicals. This review intends to give illustrative examples in this field with a special focus on scalable chemical production using enzymes. It also discusses the opportunities and limitations of enzymatic syntheses using distinct examples and provides an outlook on emerging enzyme classes.