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Active and Unidirectional Acceleration of Biaryl Rotation by a Molecular Motor
Author(s) -
Uhl Edgar,
Mayer Peter,
Dube Henry
Publication year - 2020
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.201913798
Subject(s) - molecular motor , rotation (mathematics) , acceleration , degeneracy (biology) , energy (signal processing) , potential energy , chemical energy , covalent bond , mechanical energy , chemical physics , chemistry , physics , nanotechnology , materials science , computer science , atomic physics , power (physics) , classical mechanics , quantum mechanics , artificial intelligence , bioinformatics , organic chemistry , biology
Light‐driven molecular motors possess immense potential as central driving units for future nanotechnology. Integration into larger molecular setups and transduction of their mechanical motions represents the current frontier of research. Herein we report on an integrated molecular machine setup allowing the transmission of potential energy from a motor unit onto a remote receiving entity. The setup consists of a motor unit connected covalently to a distant and sterically encumbered biaryl receiver. By action of the motor unit, single‐bond rotation of the receiver is strongly accelerated and forced to proceed unidirectionally. The transmitted potential energy is directly measured as the extent to which energy degeneration is lifted in the thermal atropisomerization of this biaryl. Energy degeneracy is reduced by more than 1.5 kcal mol −1 , and rate accelerations of several orders of magnitude in terms of the rate constants are achieved.