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Strain‐Promoted Cycloaddition of Cyclopropenes with o ‐Quinones: A Rapid Click Reaction
Author(s) -
Gahtory Digvijay,
Sen Rickdeb,
Kuzmyn Andriy R.,
Escorihuela Jorge,
Zuilhof Han
Publication year - 2018
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.201800937
Subject(s) - click chemistry , cycloaddition , chemistry , monolayer , surface modification , kinetics , photochemistry , combinatorial chemistry , organic chemistry , catalysis , biochemistry , physics , quantum mechanics
Novel click reactions are of continued interest in fields as diverse as bio‐conjugation, polymer science and surface chemistry. Qualification as a proper “click” reaction requires stringent criteria, including fast kinetics and high conversion, to be met. Herein, we report a novel strain‐promoted cycloaddition between cyclopropenes and o ‐quinones in solution and on a surface. We demonstrate the “click character” of the reaction in solution and on surfaces for both monolayer and polymer brush functionalization.