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Directed Evolution: Bringing New Chemistry to Life
Author(s) -
Arnold Frances H.
Publication year - 2018
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.201708408
Subject(s) - reactivity (psychology) , chemistry , directed evolution , computational biology , biochemical engineering , nanotechnology , combinatorial chemistry , biochemistry , biology , engineering , materials science , medicine , alternative medicine , pathology , mutant , gene
Tailor‐made : Discussed herein is the ability to adapt biology's mechanisms for innovation and optimization to solving problems in chemistry and engineering. The evolution of nature's enzymes can lead to the discovery of new reactivity, transformations not known in biology, and reactivity inaccessible by small‐molecule catalysts.