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Rhodium‐Catalyzed Decarbonylative Borylation of Aromatic Thioesters for Facile Diversification of Aromatic Carboxylic Acids
Author(s) -
Ochiai Hidenori,
Uetake Yuta,
Niwa Takashi,
Hosoya Takamitsu
Publication year - 2017
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.201611974
Subject(s) - borylation , rhodium , catalysis , chemistry , carboxylic acid , organic chemistry , aryl , alkyl
Transformation of aromatic thioesters into arylboronic esters was achieved efficiently using a rhodium catalyst. The broad functional‐group tolerance and mild conditions of the method have allowed for the two‐step decarboxylative borylation of a wide range of aromatic carboxylic acids, including commercially available drugs.