Premium
Increasing the Complexity of Periodic Protein Nanostructures by the Rolling‐Circle‐Amplified Synthesis of Aptamers
Author(s) -
Cheglakov Zoya,
Weizmann Yossi,
Braunschweig Adam B.,
Wilner Ofer I.,
Willner Itamar
Publication year - 2007
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.200703688
Subject(s) - rolling circle replication , aptamer , template , dna , nanotechnology , colloidal gold , nanostructure , nanoparticle , materials science , chemistry , biophysics , biology , microbiology and biotechnology , biochemistry , polymerase
The biomachinery of rolling‐circle amplification relying on protein–aptamer interactions on DNA scaffolds was used to create one‐dimensional DNA–protein/DNA–protein–nanoparticle hierarchical assemblies. These conjugates can serve as further templates for the immobilization of gold nanoparticles.