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Intramolecular Interactions of a Phenyl/Perfluorophenyl Pair in the Formation of Supramolecular Nanofibers and Hydrogels
Author(s) -
Hsu ShuMin,
Lin YuChun,
Chang JuiWen,
Liu YuHao,
Lin HsinChieh
Publication year - 2014
Publication title -
angewandte chemie
Language(s) - English
Resource type - Journals
eISSN - 1521-3757
pISSN - 0044-8249
DOI - 10.1002/ange.201307500
Subject(s) - moiety , intramolecular force , nanofiber , supramolecular chemistry , self healing hydrogels , chemistry , polymer chemistry , nanotechnology , materials science , stereochemistry , molecule , organic chemistry
Abstract A new system for the incorporation of a phenyl/perfluorophenyl pair in the structure of a peptide hydrogelator was developed. The strategy is based on the idea that the integration of an end‐capped perfluorophenyl group and a phenylalanine with a phenyl moiety in the side chain forms an intramolecular phenyl/perfluorophenyl pair, which can be used to promote the formation of the supramolecular nanofibers and hydrogels. This work illustrates the importance of structure‐hydrogelation relationship and provides new insights into the design of self‐assembly nanobiomaterials.