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Insular Stimulation Produces Mental Clarity and Bliss
Author(s) -
Nencha Umberto,
Spinelli Laurent,
Vulliemoz Serge,
Seeck Margitta,
Picard Fabienne
Publication year - 2022
Publication title -
annals of neurology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 4.764
H-Index - 296
eISSN - 1531-8249
pISSN - 0364-5134
DOI - 10.1002/ana.26282
Subject(s) - insula , epilepsy , neuroscience , stimulation , psychology , bliss , aura , deep brain stimulation , medicine , psychiatry , parkinson's disease , disease , migraine , computer science , programming language
For the first time, an ecstatic aura has been evoked through the electrical stimulation of the dorsal anterior insula during presurgical invasive intracerebral monitoring in a patient who did not suffer from an ecstatic form of epilepsy. This case provides more evidence that the anterior insula is the major generator of such a mystical‐type experience even in individuals with no underlying brain network changes related to a preexisting ecstatic epilepsy. ANN NEUROL 2022;91:289–292