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Iron deficiency across chronic inflammatory conditions: International expert opinion on definition, diagnosis, and management
Author(s) -
Cappellini Maria Domenica,
CominColet Josep,
de Francisco Angel,
Dignass Axel,
Doehner Wolfram,
Lam Carolyn S.,
Macdougall Iain C.,
Rogler Gerhard,
Camaschella Clara,
Kadir Rezan,
Kassebaum Nicholas J.,
Spahn Donat R.,
Taher Ali T.,
Musallam Khaled M.
Publication year - 2017
Publication title -
american journal of hematology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.456
H-Index - 105
eISSN - 1096-8652
pISSN - 0361-8609
DOI - 10.1002/ajh.24820
Subject(s) - medicine , iron deficiency , intensive care medicine , inflammatory bowel disease , anemia , disease , kidney disease , expert opinion , concomitant , chronic disease , iron deficiency anemia , anemia of chronic disease , quality of life (healthcare) , nursing
Iron deficiency, even in the absence of anemia, can be debilitating, and exacerbate any underlying chronic disease, leading to increased morbidity and mortality. Iron deficiency is frequently concomitant with chronic inflammatory disease; however, iron deficiency treatment is often overlooked, partially due to the heterogeneity among clinical practice guidelines. In the absence of consistent guidance across chronic heart failure, chronic kidney disease and inflammatory bowel disease, we provide practical recommendations for iron deficiency to treating physicians: definition, diagnosis, and disease‐specific diagnostic algorithms. These recommendations should facilitate appropriate diagnosis and treatment of iron deficiency to improve quality of life and clinical outcomes.