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Glycotherapy: A Glycotherapeutic Approach to Functionalize Biomaterials‐Based Systems (Adv. Funct. Mater. 44/2020)
Author(s) -
Gadekar Anuja,
Bhowmick Sirsendu,
Pandit Abhay
Publication year - 2020
Publication title -
advanced functional materials
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 6.069
H-Index - 322
eISSN - 1616-3028
pISSN - 1616-301X
DOI - 10.1002/adfm.202070290
Subject(s) - glycoconjugate , glycan , materials science , lectin , glycoprotein , nanotechnology , biophysics , biochemistry , chemistry , biology
In article number 1910031, Sirsendu Bhowmick, Abhay Pandit, and Anuja Gadekar discuss glycotherapeutics, which can be broadly divided into two subclasses—glycoconjugates as therapeutics and as systems for therapeutic applications. The targetability of glycotherapeutics involves the interplay of glycoconjugates and lectin interactions. On the cell surface, glycans can be found attached to proteins and lipids in the form of glycoproteins, proteoglycans, and glycosphingolipids. Lectins show a specific binding ability towards carbohydrate moieties.