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Use of Intraarticular Hyaluronic Acid in the Management of Knee Osteoarthritis in Clinical Practice
Author(s) -
Cooper Cyrus,
Rannou François,
Richette Pascal,
Bruyère Olivier,
AlDaghri Nasser,
Altman Roy D.,
Brandi Maria Luisa,
Collaud Basset Sabine,
HerreroBeaumont Gabriel,
Migliore Alberto,
Pavelka Karel,
Uebelhart Daniel,
Reginster JeanYves
Publication year - 2017
Publication title -
arthritis care and research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.032
H-Index - 163
eISSN - 2151-4658
pISSN - 2151-464X
DOI - 10.1002/acr.23204
Subject(s) - medicine , osteoarthritis , adverse effect , methylprednisolone acetate , viscosupplementation , population , diabetes mellitus , rheumatoid arthritis , acetaminophen , corticosteroid , anesthesia , surgery , alternative medicine , pathology , environmental health , intra articular , endocrinology
This review emphasizes the safety profile of intra-articular hyaluronic acid treatment of knee osteoarthritis, as well as its moderate but real efficacy on symptoms, which is in the same range than other pharmacological modalities used in this indication. Effectiveness of intra-articular hyaluronic acid has also been highlighted based on ‘real-life' data, together with the clinical benefit of systematic repeated treatment cycles, and the influence of the molecular weight of hyaluronic acid on treatment outcome. These aspects should be particularly helpful to clinicians when making personalized care decisions.