English (United Kingdom)

https://curated-unify.zendy.io/wp-json/zendy-region/v1/featured_content/oa?rat=en

https://curated-unify.zendy.io/wp-json/zendy-region/v1/highlighted_journal/

Zendy Plus

Presents the access of premium content as premium feature

Premium Content

Presents the keyphrase highlighting as premium feature

Keyphrase Highlighting

Presents the summarisation as premium feature

Summarisation

Insights

Presents the pdf analysis as premium feature

PDF Analysis

Presents the zaia usage as premium feature

ZAIA

Zendy Tools

Zendy Open

Objectives  To investigate the characteristics of atherosclerotic plaques in stroke‐related vascular beds and their relationship with stroke using three‐dimensional magnetic resonance ( MR ) vessel wall imaging.    Methods  Fifty‐two symptomatic patients (mean age: 56.3 ± 13.4 years; 38 males) were enrolled and underwent  MR  vessel wall imaging for stroke‐related vascular beds including intracranial and extracranial carotid arteries and aortic arch and routine  MR  imaging for brain. The maximum wall thickness (Max  WT ) and luminal stenosis of each plaque were measured. The presence/absence of atherosclerotic plaque, intraplaque hemorrhage ( IPH ), and severe stenosis (stenosis >50%) at each vascular bed and acute ischemic lesion ( AIL ) were determined. The correlation between Max  WT  of each vascular bed and  AIL  was analyzed.    Results  Of 52 patients, 24 (46.2%) had  AIL s, and 30 (57.7%), 34 (65.4%), and 11 (21.2%) had plaques in intracranial artery, extracranial carotid artery, and aortic arch, respectively. The prevalence of  IPH  and severe stenosis was 25% and 26.9% for intracranial arteries, 13.5% and 9.6% for extracranial carotid artery, and 3.8% and 0% for aortic arch, respectively. In discriminating  AIL , Max  WT  of intracranial artery had the highest area‐under‐the‐curve ( AUC  = 0.84), followed by extracranial carotid artery ( AUC  = 0.83) and aortic arch ( AUC  = 0.78) after adjusted for confounding factors. The  AUC  of Max  WT  combined three stroked‐related vascular beds reached 0.87.    Conclusion  Extracranial carotid arteries have the highest prevalence of plaques and intraplaque hemorrhage and severe stenosis are most frequently seen in intracranial arteries in Asian symptomatic patients. The Max  WT  combined three stroke‐related vascular beds show stronger predictive value for  AIL  than each vascular bed alone.

Atherosclerosis in stroke‐related vascular beds and stroke risk: A 3‐D MR vessel wall imaging study