Open AccessNeural coupling of cooperative hand movements after stroke: role of ipsilateral afference
Author(s) -
SchraflAltermatt Miriam,
Dietz Volker
Publication year - 2016
Publication title -
annals of clinical and translational neurology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.824
H-Index - 42
ISSN - 2328-9503
DOI - 10.1002/acn3.363
Subject(s) - medicine , stroke (engine) , somatosensory system , neuroscience , stimulation , somatosensory evoked potential , physical medicine and rehabilitation , laterality , anatomy , anesthesia , audiology , psychology , physics , psychiatry , thermodynamics
We investigated the role of ipsilateral ascending pathways in the neural coupling underlying cooperative hand movements of stroke subjects. Ipsi‐ and contralateral somatosensory evoked potentials (SSEP) were recorded following ulnar nerve stimulation during cooperative and non‐cooperative hand movements. The amplitude ratio, that is, ipsilateral divided by contralateral amplitude, was highest during the cooperative task when the affected arm was stimulated, reflecting an enhanced afferent volley to the unaffected hemisphere. The presence of ipsilateral SSEP from the paretic arm was closely related with the patients' hand function. This shows for the first time a laterality in ascending pathways after unilateral stroke and implies an involvement of the unaffected hemisphere in the control of paretic hand movements.