Open AccessProgressing small vessel pontine infarction includes different etiologies
Author(s) -
Nakase Taizen,
Sasaki Masahiro,
Ikeda Yasuko,
Suzuki Akifumi
Publication year - 2014
Publication title -
annals of clinical and translational neurology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.824
H-Index - 42
ISSN - 2328-9503
DOI - 10.1002/acn3.25
Subject(s) - medicine , etiology , infarction , pathology , myocardial infarction , cardiology
Background The aim of this study was to investigate the clinical features of progressing stroke of pontine infarction as small vessel disease. Methods Enrolled 38 acute pontine infarctions were confirmed by magnetic resonance imaging and magnetic resonance angiography at the first and seventh days. Ten patients (26.3%) presented progression ( NIH Stroke Scale ≥2 increase within 72 h). Results Progressing patients showed no relation to the size and the distribution of lesion. Expansion of ischemic lesion showed correlation with basilar artery atherosclerosis. Stable lesion related to delayed worsening. Conclusion These findings suggest that progressing stroke may be caused by not only the worsening of blood flow of ischemic lesion but also delayed neuronal death.