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Exploring the developing brain is a major issue in understanding what enableschildren to acquire amazing abilities, and how early disruptions can lead to awide range of neurodevelopmental disorders. MRI plays a key role here byproviding a non-invasive way to link brain and behavioral changes. Severalmodalities are used in newborns and infants to characterize the properties ofthe developing brain, from growth, morphology to microstructure and functionalspecialization. Recent multi-modal studies have sought to couple complementaryMRI markers to provide a more integrated view of brain development. In thischapter, we describe successively how these approaches have made it possible toassess the early maturation of brain tissues, to link different aspects ofstructural development, and to compare structural and functional braindevelopment.

Multi-modal MRI sensitive to age: Focus on early brain development in infants