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We present the first results from a dark matter search using six Skipper-CCDsin the SENSEI detector operating at SNOLAB. With an exposure of 534.9 gram-daysfrom well-performing sensors, we select events containing 2 to 10 electron-holepairs. After aggressively masking images to remove backgrounds, we observe 55two-electron events, 4 three-electron events, and no events containing 4 to 10electrons. The two-electron events are consistent with pileup from one-electronevents. Among the 4 three-electron events, 2 appear in pixels that are likelyimpacted by detector defects, although not strongly enough to trigger our"hot-pixel" mask. We use these data to set world-leading constraints on sub-GeVdark matter interacting with electrons and nuclei.

SENSEI: First Direct-Detection Results on sub-GeV Dark Matter from SENSEI at SNOLAB