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This study investigates the biomechanical properties of breast cancer cells,focusing on the invasive MDA-MB-231 and non-invasive MCF-7 cell lines, usingphase-shifting digital holographic microscopy and an acousto-holographic systemfor non-invasive strain measurement. Findings reveal higher strain values inMDA-MB-231 cells, indicative of their aggressive, metastatic nature, comparedto lower strain values in MCF-7 cells. This variance in mechanical properties,potentially linked to distinct metabolic states and responses to externalstimuli, underscores the role of cellular mechanics in cancer progression. Thestudy advances understanding of breast cancer cell mechanics, highlightingbiomechanical analysis as a crucial tool in cancer research and potentialtherapeutic interventions.

Biomechanical Analysis Of Breast Cancer Cells: A Comparative Study Of Invasive And Non-Invasive Cell Lines Using Digital Holographic Microscopy