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Background: Given that VR is applied in multiple domains, understanding theeffects of cyber-sickness on human cognition and motor skills and the factorscontributing to cybersickness gains urgency. This study aimed to explore thepredictors of cybersickness and its interplay with cognitive and motor skills.Methods: 30 participants, 20-45 years old, completed the MSSQ and the CSQ-VR,and were immersed in VR. During immersion, they were exposed to a rollercoaster ride. Before and after the ride, participants responded to CSQ-VR andperformed VR-based cognitive and psychomotor tasks. Post-VR session,participants completed the CSQ-VR again. Results: Motion sicknesssusceptibility, during adulthood, was the most prominent predictor ofcybersickness. Pupil dilation emerged as a significant predictor ofcybersickness. Experience in videogaming was a significant predictor of bothcybersickness and cognitive/motor functions. Cybersickness negatively affectedvisuospatial working memory and psychomotor skills. Overall cybersickness',nausea and vestibular symptoms' intensities significantly decreased afterremoving the VR headset. Conclusions: In order of importance, motion sicknesssusceptibility and gaming experience are significant predictors ofcybersickness. Pupil dilation appears as a cybersickness' biomarker.Cybersickness negatively affects visuospatial working memory and psychomotorskills. Cybersickness and its effects on performance should be examined duringand not after immersion.

Examination of Cybersickness in Virtual Reality: The Role of Individual  Differences, Effects on Cognitive Functions & Motor Skills, and Intensity  Differences During and After Immersion