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We report optical trapping of laser-cooled molecules at sufficient density toobserve molecule-molecule collisions for the first time in a bulk gas. SrFmolecules from a red-detuned magneto-optical trap (MOT) are compressed andcooled in a blue-detuned MOT. Roughly 30% of these molecules are loaded into anoptical dipole trap with peak number density $n_0 \approx 3\times 10^{10}\text{ cm}^{-3}$ and temperature $T\approx40$ $\mu$K. We observe two-body losswith rate coefficient $\beta = 2.7^{+1.2}_{-0.8}\times 10^{-10} \text{ cm}^3\text{ s}^{-1}$. Achieving this density and temperature opens a path toevaporative cooling towards quantum degeneracy of laser-cooled molecules.

High density loading and collisional loss of laser cooled molecules in an optical trap