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In this pioneering study, inspired by AutoGPT, the state-of-the-artopen-source application based on the GPT-4 large language model, we develop anovel tool called AD-AutoGPT which can conduct data collection, processing, andanalysis about complex health narratives of Alzheimer's Disease in anautonomous manner via users' textual prompts. We collated comprehensive datafrom a variety of news sources, including the Alzheimer's Association, BBC,Mayo Clinic, and the National Institute on Aging since June 2022, leading tothe autonomous execution of robust trend analyses, intertopic distance mapsvisualization, and identification of salient terms pertinent to Alzheimer'sDisease. This approach has yielded not only a quantifiable metric of relevantdiscourse but also valuable insights into public focus on Alzheimer's Disease.This application of AD-AutoGPT in public health signifies the transformativepotential of AI in facilitating a data-rich understanding of complex healthnarratives like Alzheimer's Disease in an autonomous manner, setting thegroundwork for future AI-driven investigations in global health landscapes.

AD-AutoGPT: An Autonomous GPT for Alzheimer's Disease Infodemiology