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Background: The debate over daylight saving time has surged, with interestsin the effects of sunlight exposure on health. \commentnj{Prior studiessimulated daylight saving time and standard time conditions by analyzingdifferent locations within time zones and neighboring areas across time zoneborders.  Methods: We analyzed cancer incidence rates from various longitudinalpositions within time zones and at time zone borders in the contiguous UnitedStates. Using data from State Cancer Profiles (2016-2020), we analyzed totalcancer of 19 types and specific rates for eight cancers, adjusted for age andincludes all demographics. Log-linear regression is used to replicate aprevious study, and spatial regression models are employed to explorediscontinuities at borders.  Results: Cancer rate differences lack statistical significance within timezones and near borders for total cancer and most individual cancers. Exceptionsincluded breast, prostate, and liver \& bile duct cancers, which exhibitedsignificant relationships with relative position at the 95\% significancelevel. Breast and liver and bile duct cancers saw decreases, while prostatecancer incidence increased from west to east within time zones.  Conclusions: Relative position does not have a significant impact on cancerincidence, hence cancer development in general. Isolated exceptions may warrantfurther investigation as more data becomes available.  Impact: Our findings challenge prior research, revealing numerousinconsistencies. These disparities urge a reconsideration of the potentialdisparities in human health associated with daylight saving time and standardtime. They offer insights contribute to the ongoing discussion surrounding theretention or abandonment of DST.

Longitudinal Position and Cancer Risk in the United States Revisited