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Pediatric tumors of the central nervous system are the most common cause ofcancer-related death in children. The five-year survival rate for high-gradegliomas in children is less than 20\%. Due to their rarity, the diagnosis ofthese entities is often delayed, their treatment is mainly based on historictreatment concepts, and clinical trials require multi-institutionalcollaborations. The MICCAI Brain Tumor Segmentation (BraTS) Challenge is alandmark community benchmark event with a successful history of 12 years ofresource creation for the segmentation and analysis of adult glioma. Here wepresent the CBTN-CONNECT-DIPGR-ASNR-MICCAI BraTS-PEDs 2023 challenge, whichrepresents the first BraTS challenge focused on pediatric brain tumors withdata acquired across multiple international consortia dedicated to pediatricneuro-oncology and clinical trials. The BraTS-PEDs 2023 challenge focuses onbenchmarking the development of volumentric segmentation algorithms forpediatric brain glioma through standardized quantitative performance evaluationmetrics utilized across the BraTS 2023 cluster of challenges. Models gainingknowledge from the BraTS-PEDs multi-parametric structural MRI (mpMRI) trainingdata will be evaluated on separate validation and unseen test mpMRI dataofhigh-grade pediatric glioma. The CBTN-CONNECT-DIPGR-ASNR-MICCAI BraTS-PEDs 2023challenge brings together clinicians and AI/imaging scientists to lead tofaster development of automated segmentation techniques that could benefitclinical trials, and ultimately the care of children with brain tumors.

The Brain Tumor Segmentation (BraTS) Challenge 2023: Focus on Pediatrics (CBTN-CONNECT-DIPGR-ASNR-MICCAI BraTS-PEDs)