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In recent decades, the development of new drugs has become increasinglyexpensive and inefficient, and the molecular mechanisms of most pharmaceuticalsremain poorly understood. In response, computational systems and networkmedicine tools have emerged to identify potential drug repurposing candidates.However, these tools often require complex installation and lack intuitivevisual network mining capabilities. To tackle these challenges, we introduceDrugst.One, a platform that assists specialized computational medicine tools inbecoming user-friendly, web-based utilities for drug repurposing. With justthree lines of code, Drugst.One turns any systems biology software into aninteractive web tool for modeling and analyzing complex protein-drug-diseasenetworks. Demonstrating its broad adaptability, Drugst.One has beensuccessfully integrated with 21 computational systems medicine tools. Availableat https://drugst.one, Drugst.One has significant potential for streamliningthe drug discovery process, allowing researchers to focus on essential aspectsof pharmaceutical treatment research.

Drugst.One -- A plug-and-play solution for online systems medicine and network-based drug repurposing