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A key challenge in Molecular Communications (MC) is low data transmissionrates, which can be addressed by channel multiplexing techniques. One way toachieve channel multiplexing in MC is to leverage the diversity of differentmolecule types with respect to their receptor binding characteristics, such asaffinity and kinetic binding/unbinding rates. In this study, we propose apractical multiplexing scheme for MC, which is based on the diversity ofligand-receptor binding affinities. This method requires only a single type ofpromiscuous receptor on the receiver side, capable of interacting with multipleligand types. We analytically derive the mean Bit Error Probability (BEP) overall multiplexed MC channels as a function of similarity among ligands in termsof their receptor affinities, the number of receptors, the number ofmultiplexed channels, and the ratio of concentrations encoding bit-1 and bit-0.We investigate the impact of each design parameter on the performance ofmultiplexed MC system.

Affinity-Division Multiplexing for Molecular Communications with Promiscuous Ligand Receptors