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Background: Total-Body imaging offers high sensitivity, single-bed position,and low dose, but high construction costs limit worldwide utilization. Thisstudy compares existing and developing tomographs using plastic scintillatorsvia simulations to propose a cost-efficient Total-Body PET scanner.  Methods: Simulations of eight uEXPLORER tomographs with differentscintillator materials, axial field-of-view, and detector configuration, andeight J-PET scanners with various field-of-view, plastic scintillatorcross-sections, and layers were performed. Biograph Vision was also simulated.Two types of simulations were conducted with a central source and awater-filled phantom.  Results: BGO crystal-based scanners showed the best sensitivity (350 cps/kBqat the center). Sparse geometry or LYSO crystals reduced sensitivity. J-PETdesign showed similar sensitivity to sparse LYSO detectors, with full bodycoverage and additional gain for brain imaging.  Conclusion: The J-PET tomography system using plastic scintillators could bea cost-efficient alternative for Total-Body PET scanners, overcoming highconstruction costs while maintaining sensitivity

Comparative studies of the sensitivities of sparse and full geometries of Total-Body PET scanners built from crystals and plastic scintillators