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Ptychography is a computational imaging technique that has risen inpopularity in the x-ray and electron microscopy communities in the past halfdecade. One of the reasons for this success is the development of new highperformance electron detectors with increased dynamic range and readout speed,both of which are necessary for a successful application of this technique.Despite the advances made in computing power, processing the recorded dataremains a challenging task, and the growth in data rate has made the size ofthe resulting datasets a bottleneck for the whole process. Here we present aninvestigation into lossy compression methods for electron diffraction patternsthat retain the necessary information for ptychographic reconstructions, yetlead to a decrease in data set size by three or four orders of magnitude. Weapply several compression methods to both simulated and experimental data - allwith promising results.

Lossy Compression of Electron Diffraction Patterns for Ptychography via Change of Basis