English (United Kingdom)

https://curated-unify.zendy.io/wp-json/zendy-region/v1/featured_content/oa?rat=en

https://curated-unify.zendy.io/wp-json/zendy-region/v1/highlighted_journal/

Zendy Plus

Presents the access of premium content as premium feature

Premium Content

Presents the keyphrase highlighting as premium feature

Keyphrase Highlighting

Presents the summarisation as premium feature

Summarisation

Insights

Presents the pdf analysis as premium feature

PDF Analysis

Presents the zaia usage as premium feature

ZAIA

Zendy Tools

Zendy Open

The existence of acoustic pulse propagation in lipid monolayers at theair-water interface is well known. These pulses are controlled by thethermodynamic state of the lipid membrane. Nevertheless, the role of acousticpulses for intra- and intercellular communication are still a matter of debate.Herein, we used the dye di 4- -ANEPPDHQ, which is known to be sensitive to thephysical state and transmembrane potential of membranes, in order to gaininsight into compression waves in lipid-based membrane interfaces. The dye wasincorporated into lipid monolayers made of phosphatidylserine orphosphatidylcholine at the air-water-interface. A significant blue shift of theemission spectrum was detected when the state of the monolayer was changed fromthe liquid expanded (LE) to the liquid condensed (LC) phase. Thistransition-sensitivity of di-4-ANEPPDHQ was generalized in experiments with thebulk solvent dimethyl sulfoxide (DMSO). Upon crystallization of solvent, theemission spectrum also underwent a blue shift. During compression pulses inlipid monolayers, a significant fluorescence response was only observed when inthe main transition regime. The optical signature of these waves, in terms ofsign and magnitude, was identical to the response of di-4-ANEPPDHQ duringaction potentials in neurons and excitable plant cells. These findingscorroborated the suggestion that action potentials are nonlinear state changesthat propagate in the cell membrane.

Unitary response of solvatochromic dye to pulse excitation in lipid and cell membranes