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Purpose: To develop a Monte Carlo (MC) therapeutic dose calculation toolkitof a recently released ring gantry linac in Geant4 (Version 10.7) for secondarydose validation of radiotherapy plan. Methods: For the Halcyon (Varian MedicalSystems), the DSMLC was modeled and radiation transport in DSMLC and patientphantom was simulated using Geant4. Radiation source was sampled from a phasespace file for linac head above the DSMLC. The phase space file was obtainedusing a cloud-based Monte Carlo (MC) simulator, VirtuaLinac (VL) provide byVarian. Dosimetric profiles for different square field widths (2x2, 4x4, 6x6,8x8, 10x10, 20x20, and 28x28 cm2), i.e., percent depth dose (PDD) curves andlateral profiles are simulated and compared against the experimental profiles.IMRT (intensity modulated radiation therapy) plans in two anatomical sites(prostate and brain) were also calculated using the developed toolkit andcompared against the TPS calculated dose (Acuros, Eclipse 15.6). 3D dosedifference and 3D gamma analysis were used to evaluate the simulation accuracycompared against the TPS calculated dose. Results: The simulated lateral doseprofiles and PDD curves in water phantom match well with the measured ones forall the simulated field sizes with relative difference +-2%. For the prostateand brain IMRT plans, the simulated dose showed a good agreement with the TPScalculated dose. The 3D gamma pass rate (3%/3mm) are 98.08% and 95.4% for thetwo prostate and brain plans, respectively. Conclusion: The developed full MCdose calculation toolkit for Halcyon performs well in dose calculations inwater phantom and patient CT phantom. The developed toolkit shows promisingpossibility for future secondary dose calculation for IMRT and serve asclinical quality assurance (QA) tool for Halcyon.

Development of a Full Monte Carlo Therapeutic Dose Calculation Toolkit for Halcyon Using Geant4