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The purpose of this paper is to prove pointwise inequalities and to establishthe boundedness on weighted $L^{p}$ spaces for pseudo-differential operators$T_{a}$ defined by the symbol $a\in S^{m}_{\varrho,\delta}$ with$0\leq\varrho\leq1,$ $0\leq\delta<1$.  Firstly, we prove that if $m\leq-n(1-\varrho)/2$, then$$(T_{a}u)^{\sharp}(x)\lesssim M(|u|^{2})^{1/2}(x)$$ for all$x\in\mathbb{R}^{n}$ and all Schwartz function $u$. Secondly, it is shown thatif $1\leq r\leq2$ and $m\leq-\frac{n}{r}(1-\varrho)$, then for any $\omega$belongs to the class of Muckenhoupt weights $A_{p/r}$ with $r<p<\infty$, theseoperators are bounded on $L^{p}_\omega$. Moreover, these results are sharp onthe bound of $m$.

Sharp function and weighted $L^{p}$ estimates for pseudo-differential operators with symbols in general H\"{o}rmander classes