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Background: It is not established whether clinical notes provided onpathology request forms are useful as decision support data when assessingHepatitis B and C viral infection status. Objective: To determine sensitivity,specificity, and predictive value of clinical notes for identifying infectionstatus of Hepatitis B and C. Methods: The study comprises 179 cases and 166cases tested for HBsAg and anti-HCV serological markers, respectively, andaccompanied by a written description (clinical note) provided on pathologyrequest forms by the clinician on duty. The clinical note sensitivity,specificity, positive (PPV) and negative (NPV) predictive values werecalculated using serological HBsAg and anti-HCV tests as gold standards.Results: The sensitivity and specificity of clinical notes for Hepatitis Binfection status were 90 percent and 56 percent, respectively. The sensitivityand specificity of clinical notes for Hepatitis C infection status were 86percent and 21 percent, respectively. Conclusions: Clinical note informationidentifies moderate-to-high sensitivity with regards to Hepatitis B and C viralinfection status, however, given low specificity in both groups, the clinicalnote is not favourable for ruling disease in, possibly due to high rate offalse positives.

Textual analysis of clinical notes on pathology request forms to determine sensitivity and specificity of Hepatitis B and C virus infection status