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Mixed reality head-mounted displays (mxdR-HMD) have the potential tovisualize volumetric medical imaging data in holograms to provide a true senseof volumetric depth. An effective user interface, however, has yet to bethoroughly studied. Tangible user interfaces (TUIs) enable a tactileinteraction with a hologram through an object. The object has physicalproperties indicating how it might be used with multiple degrees-of-freedom. Wepropose a TUI using a planar object (PO) for the holographic medical volumevisualization and exploration. We refer to it as mxdR hologram slicer(mxdR-HS). Users can slice the hologram to examine particular regions ofinterest (ROIs) and intermix complementary data and annotations. The mxdR-HSintroduces a novel real-time ad-hoc marker-less PO tracking method that workswith any PO where corners are visible. The aim of mxdR-HS is to maintainminimum computational latency while preserving practical tracking accuracy toenable seamless TUI integration in the commercial mxdR-HMD, which has limitedcomputational resources. We implemented the mxdR-HS on a commercial MicrosoftHoloLens with a built-in depth camera. Our experimental results showed ourmxdR-HS had a superior computational latency but marginally lower trackingaccuracy than two marker-based tracking methods and resulted in enhancedcomputational latency and tracking accuracy than 10 marker-less trackingmethods. Our mxdR-HS, in a medical environment, can be suggested as a visualguide to display complex volumetric medical imaging data.

Mixed reality hologram slicer (mxdR-HS): a marker-less tangible user interface for interactive holographic volume visualization