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Perineural invasion (PNI) by malignant tumor cells has been reported as anindependent indicator of poor prognosis in various cancers. Assessment of PNIin small nerves on glass slides is a labor-intensive task. In this study, wepropose an algorithm to detect the perineural invasions in colon, prostate, andpancreas cancers based on a convolutional neural network (CNN).

Perineural Invasion Detection in Multiple Organ Cancer Based on Deep Convolutional Neural Network