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The well-posedness and regularity estimates in initial distributions arederived for singular McKean-Vlasov SDEs, where the drift contains a locallystandard integrable term and a superlinear term in the spatial variable, and isLipchitz continuous in the distribution variable with respect to a weightedvariation distance. When the superlinear term is strengthened to be Lipschitzcontinuous, Wangs Harnack inequality is established. These results are new alsofor the classical Ito SDEs where the coefficients are distribution independent.

Singular McKean-Vlasov SDEs: Well-Posedness, Regularities and Wangs Harnack Inequality