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Besides maintaining health precautions, vaccination has been the onlyprevention from SARS-CoV-2, though no clinically proved 100% effective vaccinehas been developed till date. At this stage, to withhold the debris of thispandemic, experts need to know the impact of the vaccine efficacy rate'sthreshold and how long this pandemic may extent with vaccines that havedifferent efficacy rates. In this article, a mathematical model study has beendone on the importance of vaccination and vaccine efficiency rate during anongoing pandemic. We simulated a five compartment mathematical model to analyzethe pandemic scenario in both California, and whole U.S. We considered fourvaccines, Pfizer, Moderna, AstraZeneca, and Johnson and Johnson, which arebeing used rigorously to control the COVID-19 pandemic, in addition with twospecial cases: a vaccine with 100% efficacy rate and no vaccine under use. Boththe infection and death rates are very high in California. Our model suggeststhat the pandemic situation in California will be under control in the lastquartile of the year 2023 if frequent vaccination is continued with the Pfizervaccine. During this time, six waves will happen from the beginning of theimmunization where the case fatality and recovery rates will be 1.697% and98.30%, respectively. However, according to the considered model, this periodmight be extended to the mid of 2024 when vaccines with lower efficacy ratesare used. The more effective a vaccine, the less people suffer from this maligninfection. Although specific groups of people get prioritized initially, massvaccination is needed to control the spread of the disease.

Vaccine efficacy and SARS CoV 2 control in California and USA during the session 2020 2026: A modeling study