English (United Kingdom)

https://curated-unify.zendy.io/wp-json/zendy-region/v1/featured_content/oa?rat=en

https://curated-unify.zendy.io/wp-json/zendy-region/v1/highlighted_journal/

Global: Zendy Tools annual

Presents the keyphrase highlighting as premium feature

Keyphrase Highlighting

Presents the summarisation as premium feature

Summarisation

Insights

Presents the pdf analysis as premium feature

PDF Analysis

Presents the zaia usage as premium feature

ZAIA

Global: Zendy Tools monthly

Global: Zendy Plus monthly

Presents the access of premium content as premium feature

Premium Content

Global: Zendy Plus annual

Global: Zendy Free Plan

Nanotechnology has been one of the fastest growing fields in the last threedecades. Nanomaterials (sized 1-100 nm) has a wide spectrum of potentialapplications in many fields, applied as coating materials or in treatment anddiagnosis. Nowadays, nanoparticles of both metallic and non-metallic origin areunder investigation and development for applications in various fields ofbiology/therapeutics. Specifically, we show the correlations between thephysicochemistry and biophysical specificity of metal nanoparticles and theiruptake, transport, and biodistribution in cells, at the molecular, cellular,and whole organism level. Physiologically important metals are present in thehuman body with a wide range of biological activities. Some of these metals aremagnesium, chromium, manganese, iron, cobalt, copper, zinc, selenium andmolybdenum. Metals used in nanotechnology have to be biocompatible with thehuman system in terms of absorption, assimilation, excretion, and side effects.These metals are synthesized in the form of nanoparticles by different physicaland chemical methods. Nanotoxicological studies of metal nanoparticles areintended to determine whether and to what extent their properties may pose athreat to the environment and to human beings. An overview of metal and metaloxide nanoparticles, their applications, and the potential for human exposureis provided, and it is integrated by a discussion of general principles ofnanoparticle-induced toxicity and methods for toxicity testing ofnanomaterials. This review wants to focus on establishing metal nanoparticlesof physiological importance to be the best candidates for futurenanotechnological tools and medicines, owing to the acceptability and safety inthe human body. This can only be successful if these particles are synthesizedwith a better biocompatibility and low or no toxicity.

Biophysical interaction, nanotoxicology evaluation, and biocompatibility and biosafety of metal nanoparticles