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Complex thermodynamics of the human body and external factors may causedifferences between oral and core body temperatures. We present a 19-subjectstudy where continuous measurements of ingested core temperature pills arecompared against spot measurements of oral temperature, both FDA-cleareddevices, in free-living conditions. Based on measurements from 419 samplesacross 19 subjects, MAE of 0.30 +/- 0.26 oC and 95% limits of agreement of-0.60 and 0.90 oC was observed between ingestible pill temperature and oraltemperature. These results demonstrate that statistically significantdifferences (p<0.001) between oral and core temperature may arise infree-living conditions. Such clinically relevant differences in temperaturemeasurements due to complex thermodynamics of heat exchange in the human body,measurement noise, and other external factors show the intricacies ofinterpreting body temperatures measured at different locations.

Validity and reliability of oral temperature compared to ingestible core temperature pill in free-living conditions