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The next-generation sequencers such as Illumina and SOLiD platforms generatea large amount of data, commonly above 10 Gigabytes of text files.Particularly, the SOLiD platform allows the sequencing of multiple samples in asingle run, called multiplex run, through a tagging system called Barcode. Thisfeature requires a computational process for separation of the data samplebecause the sequencer provides a mixture of all samples in a single output.This process must be secure to avoid any harm that may scramble furtheranalysis. In this context, realized the need to develop a probabilistic modelcapable of assigning a degree of confidence in the marking system used inmultiplex sequencing. The results confirmed the adequacy of the model obtained,which allows, among other things, to guide a process of filtering the data andevaluation of the sequencing protocol used.

Abordagem probabil\'istica para an\'alise de confiabilidade de dados gerados em sequenciamentos multiplex na plataforma ABI SOLiD