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The BraTS 2021 challenge celebrates its 10th anniversary and is jointlyorganized by the Radiological Society of North America (RSNA), the AmericanSociety of Neuroradiology (ASNR), and the Medical Image Computing and ComputerAssisted Interventions (MICCAI) society. Since its inception, BraTS has beenfocusing on being a common benchmarking venue for brain glioma segmentationalgorithms, with well-curated multi-institutional multi-parametric magneticresonance imaging (mpMRI) data. Gliomas are the most common primarymalignancies of the central nervous system, with varying degrees ofaggressiveness and prognosis. The RSNA-ASNR-MICCAI BraTS 2021 challenge targetsthe evaluation of computational algorithms assessing the same tumorcompartmentalization, as well as the underlying tumor's molecularcharacterization, in pre-operative baseline mpMRI data from 2,040 patients.Specifically, the two tasks that BraTS 2021 focuses on are: a) the segmentationof the histologically distinct brain tumor sub-regions, and b) theclassification of the tumor's O[6]-methylguanine-DNA methyltransferase (MGMT)promoter methylation status. The performance evaluation of all participatingalgorithms in BraTS 2021 will be conducted through the Sage Bionetworks Synapseplatform (Task 1) and Kaggle (Task 2), concluding in distributing to the topranked participants monetary awards of $60,000 collectively.

The RSNA-ASNR-MICCAI BraTS 2021 Benchmark on Brain Tumor Segmentation and Radiogenomic Classification