English (United Kingdom)

https://curated-unify.zendy.io/wp-json/zendy-region/v1/featured_content/oa?rat=en

https://curated-unify.zendy.io/wp-json/zendy-region/v1/highlighted_journal/

Global: Zendy Tools annual

Presents the keyphrase highlighting as premium feature

Keyphrase Highlighting

Presents the summarisation as premium feature

Summarisation

Insights

Presents the pdf analysis as premium feature

PDF Analysis

Presents the zaia usage as premium feature

ZAIA

Global: Zendy Tools monthly

Global: Zendy Plus monthly

Presents the access of premium content as premium feature

Premium Content

Global: Zendy Plus annual

Global: Zendy Free Plan

A key challenge in cardiology is the non-invasive imaging of electric currentpropagation occurring in the cardiovascular system at an intra-cardiac scale. Apromising approach for directly mapping the current dynamics is to monitor theassociated stray magnetic field. However, in this magnetic field approach, thespatial resolution deteriorates significantly as the standoff distance betweenthe target and the sensor increases. Existing sensors usually remain relativelyfar from the target and provide only centimetre-scale resolution because theiroperating temperature is not biocompatible. Here we demonstratemillimetre-scale magnetocardiography of living rats using a solid-state quantumsensor based on nitrogen-vacancy centres in diamond. The essence of the methodis a millimetre proximity from the sensor to heart surface, which enhances thecardiac magnetic field to greater than nanoteslas and allows the mapping ofthese signals with intra-cardiac resolution. From the acquired magnetic images,we also estimate the source electric current vector, flowing from the rightatria base via the Purkinje fibre bundle to the left ventricular apex. Ourresults establish the solid-state quantum sensor's capability to probe cardiacmagnetic signals from mammalian animals and reveal their intra-cardiacelectrodynamics. This technique will enable the study of the origin andprogression of myriad cardiac arrhythmias including flutter, fibrillation, andtachycardia.

Millimetre-scale magnetocardiography of living rats using a solid-state quantum sensor