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Many countries are managing COVID-19 epidemic by switching between lighterand heavier restrictions. While an open-close and a close-open cycle havecomparable socio-economic costs, the former leads to a much heavier burden interms of deaths and pressure on the healthcare system. An empiricaldemonstration of the toll ensuing from procrastination was recently observed inIsrael, where both cycles were enforced from late August to mid-December 2020,yielding some 1,600 deaths with open-close compared to 440 with close-open.

Preemptive periodic epidemic control reduces life and healthcare system costs without aggravation of social and economic losses