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While facial coverings over the nose and mouth reduce the spread of the virusSARS-CoV-2 by filtration, masks capable of viral inactivation by heating couldprovide a complementary method to limit viral transmission. In this work, weintroduce a new virucidal face mask concept based on a reverse-flow reactordriven by the oscillatory flow of human breath. The governing heat and masstransport equation are formulated and solved to analyze designs that evaluateboth viral and CO2 transport during inhalation and exhalation. Given limitsimposed by the volume and frequency of human breath, the kinetics of SARS-CoV-2thermal inactivation, and human safety and comfort, heated masks may inactivateSARS-CoV-2 in inflow and outflow to medical grade sterility. We detail oneparticular design, with a volume of 300 mL at 90 $^\circ$C, that achieves a3-log reduction in viral load with minimal viral impedance within the maskmesh, with partition coefficient around 2. This study is the first quantitativeanalysis of virucidal thermal inactivation within a protective face mask andaddresses a pressing need for new approaches for personal protective equipmentduring a global pandemic.

A Virucidal Face Mask Based on the Reverse-flow Reactor Concept for Thermal Inactivation of SARS-CoV-2