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In chemistry, biology and materials science, the ability to accessinteratomic interactions and their dynamical evolution has become possible withthe advent of femtosecond lasers. In particular, the observation of vibrationalwave packets via optical (UV-visible-IR) spectroscopies has been a majorachievement as it can track the motion of nuclei within the system. However,optical spectroscopies only detect the effect of the interatomic vibrations onthe global electronic surfaces. New tuneable, pulsed and polarized sources ofshort-wavelength radiation, such as X-Ray Free electron lasers, can overcomethis limitation, allowing for chemical and, of primary importance inbiochemistry, enantiomeric selectivity. This selectivity may be complemented bytaking into account the chemical shifts of atoms belonging to differentmolecular moieties

Element- and enantiomer-selective visualization of ibuprofen dimer vibrations