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Heavy quarks are effective probes of the hot and dense nuclear matter, thequark-gluon plasma, produced in ultra-relativistic heavy-ion collisions. Due tothe short time scale characterising their production, heavy quarks experiencethe whole evolution of the system. In particular, measurements of heavy-flavourhadron production in Pb-Pb collisions at LHC energies give insight into themechanisms of heavy-quark transport in the deconfined matter. In small hadronicsystems, pp and p-Pb collisions, heavy-flavour measurements provide thebaseline for observations of hot-medium effects in heavy-ion collisions, aswell as tests of perturbative quantum chromodynamic calculations andmeasurements of cold-nuclear-matter effects. In this contribution, recent ALICEresults on open heavy-flavour hadron production in pp, p-Pb and Pb-Pbcollisions at various energies are discussed. New measurements are presentedboth for fully-reconstructed charmed hadrons and for single electrons fromheavy-flavour hadron decays, also investigating the beauty-quark production viathe measurement of D mesons and electrons from beauty-hadron decays.

Open heavy-flavour production from small to large collision systems with ALICE at the LHC