English (United Kingdom)

https://curated-unify.zendy.io/wp-json/zendy-region/v1/featured_content/oa?rat=en

https://curated-unify.zendy.io/wp-json/zendy-region/v1/highlighted_journal/

Global: Zendy Plus annual

Presents the access of premium content as premium feature

Premium Content

Presents the keyphrase highlighting as premium feature

Keyphrase Highlighting

Presents the summarisation as premium feature

Summarisation

Insights

Presents the pdf analysis as premium feature

PDF Analysis

Presents the zaia usage as premium feature

ZAIA

Global: Zendy Plus monthly

Global: Zendy Tools annual

Global: Zendy Tools monthly

Global: Zendy Free Plan

We investigate the interplay between two fundamental mechanisms of microbialpopulation dynamics and evolution called dormancy and horizontal gene transfer.The corresponding traits come in many guises and are ubiquitous in microbialcommunities, affecting their dynamics in important ways. Recently, they haveeach moved (separately) into the focus of stochastic individual-based modelling(Billiard et al. 2016, 2018; Champagnat, M\'el\'eard and Tran, 2021; Blath andT\'obi\'as 2020). Here, we examine their combined effects in a unified model.Indeed, we consider the (idealized) scenario of two sub-populations,respectively carrying 'trait 1' and 'trait 2', where trait 1 individuals areable to switch (under competitive pressure) into a dormant state, and trait 2individuals are able to execute horizontal gene transfer, turning trait 1individuals into trait 2 ones, at a rate depending on the frequency ofindividuals. In the large-population limit, we examine the fate of a singletrait i individual (a 'mutant') arriving in a trait j resident populationliving in equilibrium, for $i,j=1,2,i \neq j$. We provide a complete analysisof the invasion dynamics in all cases where the resident population isindividually fit and the initial behaviour of the mutant population isnon-critical. We identify parameter regimes for the invasion and fixation ofthe new trait, stable coexistence of the two traits, and 'founder control'(where the initial resident always dominates, irrespective of its trait). Themost striking result is that stable coexistence occurs in certain scenarioseven if trait 2 (which benefits from transfer at the cost of trait 1) would beunfit when being merely on its own. In the case of founder control, thelimiting dynamical system has an unstable coexistence equilibrium. In allcases, we observe the classical (up to 3) phases of invasion dynamics \`a laChampagnat (2006).

The interplay of dormancy and transfer in bacterial populations: Invasion, fixation and coexistence regimes