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This study aims to introduce IViST (In Vivo Source Tracking), a novelmulti-sensors dosimetry platform for real-time treatment monitoring in HDRbrachytherapy. IViST is a platform that comprises 3 parts: 1) an optimized andcharacterized multi-point plastic scintillator dosimeter (3 points mPSD; usingBCF-60, BCF-12, and BCF-10 scintillators), 2) a compact assembly ofphotomultiplier tubes (PMTs) coupled to dichroic mirrors and filters forhigh-sensitivity scintillation light collection, and 3) a Python-basedgraphical user interface used for system management and signal processing.IViST can simultaneously measure dose, triangulate source position, and measuredwell time. By making 100 000 measurements/s, IViST samples enough data toquickly perform key QA/QC tasks such as identifying wrong individual dwell timeor interchanged transfer tubes. By using 3 co-linear sensors and plannedinformation for an implant geometry (from DICOM RT), the platform can alsotriangulate source position in real-time. A clinical trial is presentlyon-going using the IViST system.

From conception to clinical trial: IViST -- the first multi-sensor-based  platform for real-time In Vivo dosimetry and Source Tracking in HDR  brachytherapy