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Background An advantaged socioeconomic position (SEP) and satisfying socialsupport during pregnancy (SSP) have been found to be protective factors ofmaternal postpartum depression (PDD). An advantaged SEP is also associated withsatisfying SSP, making SSP a potential mediator of social inequalities in PPD.SEP, SSP and PPD are associated with migrant status. The aim of this study wasto quantify the mediating role of SSP in social inequalities in PPD regardingmother's migrant status. Methods A sub-sample of 15,000 mothers from the Frenchnationally-representative ELFE cohort study was used for the present analyses.SEP was constructed as a latent variable measured with educational attainment,occupational grade, employment, financial difficulties and household income.SSP was characterized as perceived support from partner (good relation,satisfying support and paternal leave) and actual support from midwives(psychosocial risk factors assessment and antenatal education). Mediationanalyses with multiple mediators, stratified by migrant status were conducted.Results Study population included 76% of non-migrant women, 12% of second and12% of first generation migrant. SEP was positively associated with supportfrom partner, regardless of migrant status. Satisfying partner support wasassociated with a 8 (non-migrant women) to 11% (first generation migrant women)reduction in PPD score. Limitations History of depression was notreported.Conclusions Partner support could reduce social inequalities in PPD.This work supports the need of interventions, longitudinal and qualitativestudies including fathers and adapted to women at risk of PPD to betterunderstand the role of SSP in social inequalities in PPD. Keywords socialsupport, postpartum depression, epidemiology, social inequalities, pregnancy,mediation analysis

Partner support during pregnancy mediates social inequalities in maternal postpartum depression for non-migrant and first generation migrant women