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The SARS-CoV-2 virus has resulted in a devastating pandemic of COVID-19.Exploring compounds that could offer a breakthrough in treatment is the need ofthe hour. Re-positioning cheap, freely available and safe drugs is a priority.The paper proposes evidence for the potential use of diethylcarbamazine (DEC)in the treatment of COVID-19. DEC has inhibitory effects on arachidonic acidmetabolism to prostaglandins, little known anti-viral effects on animalretroviruses and demonstrated anti-inflammatory actions in animal models oflung inflammation indicating the need to explore this hypothesis further. Webelieve this is the first time DEC is being proposed to treat COVID-19.

Is the anti-filarial drug diethylcarbamazine useful to treat COVID-19?