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Mesoscopic physics-based dual spectroscopic imaging techniques, partial wavespectroscopy (PWS) and inverse participation ratio (IPR), are used to quantifythe nano to submicron scales structural alterations in postnatal pups braincells and tissues due to fetal alcoholism. Chronic alcoholism during pregnancy,being teratogenic, results in fetal alcohol syndrome and neurological disorder.Results of PWS studies of brain tissues show a higher degree of structuralalterations. Furthermore, the IPR analyses of cell nuclei show that spatialmolecular mass density structural disorder increases in DNA while decreases forhistone. This study characterize the brain spatial structures from molecular totissue level in fetal alcoholism.

Optical probing of pups brain tissue and molecular specific nuclear  nano-structural alterations due to fetal alcoholism via dual spectroscopic  approach