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Imaging specimens over large scales and with a sub-micron resolution isinstrumental to biomedical research. Yet, the number of pixels to form such animage usually exceeds the number of pixels provided by conventional cameras.While most microscopes are equipped with a motorized stage to displace thespecimen and acquire the image tile-by-tile, we propose an alternative strategythat does not require any moving part in the sample plane. We propose to add ascanning mechanism in the detection unit of the microscope to collectsequentially different sub-areas of the field of view. Our approach, calledremote scanning, is compatible with all camera-based microscopes. We evaluatethe performances in both wide-field microscopy and full-field optical coherencetomography and we show that a field of view of 2.2 mm with 1.1 micronresolution can be achieved. We finally demonstrate that the method isespecially suited to image biological samples such as millimetric engineeredtissues.

Remote scanning for ultra-large field of view in wide-field microscopy and full-field OCT